Endocrine Abstracts

Background: Elevation of blood and tissue concentrations of glucose and advanced glycation end products (AGEs) may play a relevant role in the occurrence of atherosclerosis, arteriosclerosis and diabetic complications. To evaluate the impact of elevated extracellular AGEs and different glucose concentrations we studied the gene expressions and the underlying pathways which may lead to endothelial inflammation.Methods: Fresh human umbilical vein cord endo...